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Summary and quick links
Surplus equipment
UVA Bioconnector (description/site)
Finding research collaborators
Transgenic mice: Cre/Flox/Flp mice @UVA (Gene Targeting & Transgenic Facility)
UVA faculty with international research interests (UVA Provost site)
Resources for clinical research and use of research animals
Research core facilities
School of Medicine surplus equipment swap. Items in good or serviceable condition will be posted at this site for approximately two weeks before being sent to UVA Surplus. If you have any questions about this service, contact the Office for Research (x3-7088) or Dr. Steven Wasserman.
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UVA BioConnector. The BioConnector is a research web portal for tools in the area of bioinformatics. At this single site, users can access bioinformatics resources and tools, educational content, and collaborative technologies.
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Finding research collaborators at UVA
UVA collegiality: UVA faculty collaborate among departments, centers, and schools. Speak with your research mentor or senior faculty in your department, who can refer you to colleagues in the SOM or across Grounds who might be helpful in your research. Alternately, the Office for Research (x3-7088) may help in finding collaborators or specialized equipment to support your research.
Graduate Programs Office Research Faculty Directory:
This is a searchable directory of Biomedical Sciences Graduate Program and other research faculty at the SOM and select other UVA schools.
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Resources for clinical research and use of research animals
Center for Comparative Medicine: The University's AAALAC-accredited facility supports biomedical research utilizing animals. Services include training, veterinary support, animal housing, etc.
General Clinical Research Center: The NIH-supported GCRC has been in existence since 1968, providing inpatient and outpatient facilities, staff, and support cores for the conduct of advanced clinical research. It is located on the 8th floor of the University Hospital.
Clinical Trials Office: The CTO supports the development of proposals and protocols for clinical research, clinical coordinators, and data management, biostatistical, and QA/QC.
Clinical Data Repository: The CDR is a database facility allowing authorized researchers to access UVA health care data, including individual data from the UVA patient information systems (demographics, diagnoses, procedures, financials, patient tracking, length of stay, etc.) and comparative statewide and national datasets. Integrated into this are clinically-rich departmental datasets for selected subsets of patients. Patient identifiers are encrypted or omitted to protect patient confidentiality and privacy.
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Research Core Facilities. The School of Medicine supports several state-of-the-art core facilities that are available to investigators on a fee-for-service basis. These facilities are administered by Jay W. Fox, Ph.D., Assistant Dean for Research Support, and an advisory committee. Each core is overseen by a faculty committee; the SOM Research Advisory Committee (RAC) recommends annual subsidies to the Dean.
- Office of Research Core Administration - access the Core Facility usage and invoicing system.
- Advanced Microscopy Facility. The Advanced Microscopy Core (AMC) provided expertise, training and instrumentation associated with confocal and electron microscopy (TEM and SEM). Sample preparation and operation of core instrumentation can be performed by core staff or trained users.
- Biomolecular Research Facility. The Biomolecular Research Facility is divided into two program areas: Mass spectrometry/Proteomics and DNA Sciences. The Mass Spectrometry/Proteomics area supports experimentation in protein identification, post-translational modification analysis, binding partner/complex mixture analysis and quantitative mass spectrometry utilizing iTRAQ and SILAC approaches. The DNA Sciences Laboratory offers gene expression profiling by Affymetrix platforms, genomic analysis using a Solexa analyzer and DNA sequencing.
- BioNMR Core (Contact Jeff Ellena, Laboratory Director or Dr. John Bushweller, Faculty Director). The BioNMR Core has two NMR spectrometers (600MHz and 800MHz) for use by trained investigators or core staff. Expert consultation in molecular structural elucidation and molecular dynamics is available.
- Biorepository and Tissue Research Facility. This resource provides prospective and banked human tissue procurement; processing and storage of all types of biospecimens including blood, urine and tissues; enzymatic dissociation and freezing of tissue samples; and extraction of nucleic acids and proteins from tissues. Laser microdissection, immunohistochemistry and tissue microarray production are also available.
- Flow Cytometry Core Facility. The core maintains a variety of cell sorters and analyzers for state of the art cellular characterization. Expert consultation is available for experimental design and instrumentation is available for use by trained investigators or experiments can be performed by the staff. Several training/educational programs are offered throughout the year for investigators, students and staff.
- Gene Targeting and Transgenic Facility. The range of services offered by the GTTF include genetic engineering of mutant mice; genetic analysis of mutant mouse strains and cryopreservation of mutant lines. The facility offers a yearly educational workshop to train investigators and staff in technologies associated with genetic manipulation of mice.
- Lymphocyte Culture Center. The primary function of this core is to construct and select lymphocyte-myeloma hybridomas for the production and purification of monoclonal antibody reagents as well as expert consultation on experimental design leading to monoclonal production and antibody
characterization.
- Molecular Imaging Core. The aim of the core is to provide noninvasive monitoring of biological processes in vivo using a variety of anatomical and functional imaging modalities. Additionally development of targeted imaging agents is available. Instrumentation for the modalities of X-Ray CT, MRI, PET, SPECT and bioluminescence are available. A cyclotron will be in place within the near future.
- MolMart. This facility provides common molecular biological reagents and supplies for purchase and delivery to investigator laboratories. Reagent pick-up at the site is also available.
- Research Histology Core. The Research Histology Core offers high quality, high throughput histology services including routine embedding, sectioning and H and E and special staining protocols. This core works in close affiliation with the BTRF to coordinate efforts to support investigators.
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Tissue Culture Core. Services provide by the Tissue Culture Core include cell line culture, propagation and storage as well as primary cell culture and baculovirus production. A variety of cell culture reagents are available in the laboratory for investigator purchase.
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