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James  R.  Brookeman
Degree(s): Ph.D.
Graduate School: St. Andews University, Scotland
Primary Appointment: Professor of Research of Radiology
Research Interests:
Magnetic Resonance Investigations mainly Hyperpolarized Gas and 3D Brain Imaging

Email Address: jrb5m@virginia.edu
Biomedical Sciences Graduate Program(s)
  • Biomedical Engineering
    • Research Description

    Our research seeks to improve methods of both two-dimensional and three-dimensional magnetic resonance image acquisition for diagnosis and for the planning and development of specialized radiofrequency coils for improved imaging used in surgery. The Department of Radiology’s research laboratory is equipped with a 1.5 Tesla whole-body MR scanner. Plans are well advanced to install a new enhanced-gradient 1.5 Tesla MRI for improved cardiac and neurological studies brain imaging. Since 1996 we have pursued research in Hyperpolarized Noble Gas MR as well, employing laser-polarized Helium-3 and Xenon-129 to study lung ventilation, virtual colonoscopy, and tissue perfusion. At this time we are investigating a series of asthma and COPD subjects to evaluate the clinical potential of this new lung imaging technique.

    Selected Publications
  • J. P. Mugler, III, B. Driehuys, J. R. Brookeman, et al. MR imaging and spectroscopy using hyperpolarized 129Xe gas: preliminary human results. Magnetic Resonance in Medicine, 37: 809-815, 1997.
  • E. E. deLange, J. P. Mugler, III, J. R. Brookeman, J. Knight-Scott, et al. Lung airspaces: MR imaging evaluation with hyperpolarized 3He gas. Radiology, 210:851-857, 1999.
  • PubMed Listings for this Faculty Member
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    Contact Information
      Office Address: PO Box 801339, MR-4 Bldg, Room 1190, 
      Office Phone: +1 434-243-4969
      Fax Phone: +1 434-092-4943
      Home Phone: +1 434-979-3724

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